Toshihide Kurihara Selected Research

Retinal Pigments (Pigments, Visual)

1/2016	Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.
1/2016	The Neuroprotective Effect of Rapamycin as a Modulator of the mTOR-NF-κB Axis during Retinal Inflammation.

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Toshihide Kurihara Research Topics

Disease

27	Myopia 02/2024 - 02/2017
23	Hypoxia (Hypoxemia) 05/2024 - 05/2010
19	Inflammation (Inflammations) 05/2024 - 12/2006
16	Macular Degeneration (Age-Related Maculopathy) 05/2024 - 06/2007
15	Ischemia 05/2024 - 01/2019
13	Diabetic Retinopathy (Retinopathy, Diabetic) 05/2024 - 07/2005
11	Choroidal Neovascularization 01/2023 - 06/2007
10	Retinal Degeneration 01/2024 - 05/2008
9	Atrophy 01/2023 - 01/2019
7	Retinal Diseases 11/2022 - 03/2009
6	Vision Disorders (Hemeralopia) 05/2024 - 05/2012
6	Macular Edema 01/2023 - 07/2005
6	Blindness (Hysterical Blindness) 08/2021 - 01/2011
5	Eye Diseases (Eye Disease) 05/2024 - 05/2012
5	Uveitis 06/2021 - 12/2006
5	Pathologic Neovascularization 11/2020 - 08/2010
4	Epiretinal Membrane (Epiretinal Membranes) 12/2021 - 09/2014
4	Neoplasms (Cancer) 06/2021 - 11/2011
4	Cataract (Cataracts) 01/2021 - 12/2009
4	Retinal Neovascularization 11/2020 - 01/2019
3	Retinal Vein Occlusion 05/2024 - 01/2020
3	Refractive Errors (Refractive Error) 11/2023 - 01/2019
3	Gliosis 11/2022 - 01/2021
3	Vascular Diseases (Vascular Disease) 01/2021 - 11/2020
3	Retinal Perforations 01/2021 - 07/2005
2	Glaucoma 05/2024 - 11/2023
2	Cardiovascular Diseases (Cardiovascular Disease) 11/2022 - 08/2021
2	Pathologic Processes 11/2022 - 01/2021
2	Reperfusion Injury 09/2022 - 01/2022
2	Retinal Detachment (Retinal Detachments) 10/2021 - 09/2015
2	Edema (Dropsy) 05/2020 - 04/2017
2	Ganglion Cysts (Ganglion) 03/2020 - 12/2019
2	Polypoidal Choroidal Vasculopathy 01/2019 - 01/2016
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2023
1	Geographic Atrophy 01/2023
1	Cardiovascular Abnormalities 11/2022

Drug/Important Bio-Agent (IBA)

49	Retinaldehyde (Retinal)IBA 05/2024 - 12/2006
24	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 06/2007
10	Proteins (Proteins, Gene)FDA Link 02/2024 - 12/2006
8	Oxygen (Dioxygen)IBA 04/2023 - 08/2010
7	PPAR alphaIBA 05/2024 - 11/2019
6	(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA 01/2023 - 11/2019
6	Neuroprotective AgentsIBA 01/2021 - 12/2006
5	Ophthalmic Solutions (Eye Drops)IBA 11/2023 - 05/2021
5	CytokinesIBA 03/2023 - 03/2007
5	Transcription Factors (Transcription Factor)IBA 01/2023 - 08/2010
5	Interleukin-6 (Interleukin 6)IBA 12/2017 - 06/2007
4	AntioxidantsIBA 11/2022 - 03/2009
4	Ranibizumab (Lucentis)FDA Link 05/2020 - 01/2016
4	Therapeutic UsesIBA 01/2020 - 12/2006
4	LuteinIBA 08/2017 - 03/2009
4	Rhodopsin (Visual Purple)IBA 01/2016 - 12/2006
4	EndotoxinsIBA 01/2016 - 12/2006
3	NAD (NADH)IBA 05/2024 - 09/2022
3	OpsinsIBA 10/2023 - 01/2023
3	LactoferrinIBA 03/2023 - 01/2020
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 01/2022
3	Fenofibrate (CiL)FDA LinkGeneric 10/2021 - 11/2019
3	Indocyanine Green (Cardio-Green)FDA LinkGeneric 05/2021 - 09/2014
3	Fluorescein (Funduscein)FDA LinkGeneric 05/2021 - 07/2005
3	trans-sodium crocetinate (crocetin)IBA 01/2020 - 01/2019
3	Carotenoids (Carotene)IBA 01/2020 - 05/2012
3	ResveratrolIBA 11/2011 - 07/2009
3	SynaptophysinIBA 01/2011 - 12/2006
2	Indicators and Reagents (Reagents)IBA 05/2024 - 01/2019
2	halofuginoneIBA 01/2024 - 06/2019
2	4-phenylbutylamineIBA 01/2023 - 10/2022
2	Nicotinamide MononucleotideIBA 11/2022 - 09/2022
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2022 - 05/2008
2	Early Growth Response Protein 1IBA 01/2022 - 01/2019
2	Eicosapentaenoic AcidIBA 01/2022 - 09/2007
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2022 - 09/2007
2	Blood Glucose (Blood Sugar)IBA 10/2021 - 08/2020
2	fibroblast growth factor 21IBA 08/2021 - 11/2019
2	Atropine FDA LinkGeneric 05/2021 - 11/2019
2	Macular PigmentIBA 05/2020 - 08/2017
2	MicroRNAs (MicroRNA)IBA 07/2019 - 03/2018
2	afliberceptIBA 01/2018 - 11/2016
2	Retinal Pigments (Pigments, Visual)IBA 01/2016 - 01/2016
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2011 - 09/2008
2	Type 1 Angiotensin ReceptorIBA 01/2011 - 12/2006
2	UbiquitinIBA 01/2011 - 09/2008
2	LigandsIBA 01/2011 - 03/2007
1	bunazosin (Andante)IBA 11/2023
1	TunicamycinIBA 11/2023
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2023
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2023
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2023
1	Connexin 43 (Connexin43)IBA 01/2023
1	ElementsIBA 10/2022
1	CollagenIBA 10/2022
1	Low Density Lipoprotein Receptor-Related Protein-2IBA 09/2022

Therapy/Procedure

21	Therapeutics 01/2023 - 01/2011
6	Lenses 11/2023 - 01/2018
5	Vitrectomy 12/2021 - 07/2005
4	Lasers (Laser) 04/2020 - 01/2019
3	Intravitreal Injections 10/2023 - 09/2014
2	Eyeglasses (Spectacles) 11/2021 - 12/2020
2	Light Coagulation 10/2021 - 01/2021
1	Eye Protective Devices (Goggles) 01/2023